lunes, 6 de febrero de 2017

Nuestro último artículo, aceptado en Comparative Biochemistry and Physiology, Part A



Nuclear and membrane progestin receptors in the European eel: characterization and expression in vivo through spermatogenesis
M. Morini, D.S. Peñaranda, M.C. Vílchez, R. Nourizadeh-Lillabadi, A.G. Lafont, S. Dufour, J.F. Asturiano, F.A. Weltzien, L. Pérez

Abstract

Characterization of all the progestin receptor genes (PRs) found in the European eel has been performed. There were five membrane PRs (mPRs): mPRα (alpha), mPRAL1 (alpha-like1), mPRAL2 (alpha-like2), mPRγ (gamma), mPRδ (delta) and two nuclear PRs (nPRs or PGRs): pgr1 and pgr2. In silico studies showed that the C and E(F)  domains of Pgr are well conserved among vertebrates whereas the A/B domain is not. Phylogeny and synteny analyses suggest that eel duplicated pgr (pgr1 and pgr2) originated from the teleost-specific third whole genome duplication (3R). mPR phylogeny placed three eel mPRs together with the mPRα clade, being termed mPRα, mPRAL1 and mPRAL2, while the other two eel mPRs clustered with mPRγ and mPRδ clades, respectively.
The in vivo study showed differential expression patterns along the brain-pituitary-gonad axis. An increase in nPR transcripts was observed in brain (in pgr1) and pituitary (in pgr1 and pgr2) through the spermatogenesis, from the spermatogonia B/spermatocyte stage to the spermiation stage. In the testis, mPRγ, mPRδ and pgr2 transcripts showed the highest levels in testis with A spermatogonia as dominant germ cell, while the highest mPRα, mPRAL1 and mPRAL2 transcripts were observed in testis from spermiating males, where the dominant germ cell were spermatozoa. Further studies should elucidate the role of both nuclear and membrane progestin receptors on eel spermatogenesis.



doi: 10.1016/j.cbpa.2017.02.009

viernes, 3 de febrero de 2017

Buscamos candidatos para solicitar un contrato predoctoral



El 30 de enero la Conselleria de Educación, Investigación, Cultura y Deporte de la Generalitat Valenciana publicó en el Diari Oficial de la Generalitat Valenciana la convocatoria de subvenciones para la contratación de personal investigador de carácter predoctoral de 2017.


Se trata de ayudas de 3 años destinadas a realizar una Tesis Doctoral, y los contratados cobrarán 16.800 €/año.


La convocatoria exige tener una nota media mínima de 7.8 y haber finalizado los estudios durante los 3 años anteriores a la fecha de la convocatoria.


En el Grupo de Acuicultura y Biodiversidad de la UPV buscamos candidatos que quieran realizar una Tesis sobre tratamientos hormonales alternativos para la inducción sexual de la anguila europea.


La fecha de entrega de la documentación es el 20 de febrero y hay que preparar algunos documentos para entonces.


Si estás interesado envía tu email y tu dirección de Skype a Juan F. Asturiano (jfastu@dca.upv.es).